Review our publications

Circulating T-cell receptor repertoire analysis improves cancer early detection

Yilong Li, Michelle Nahas, Dennis Stephens, Kate Froburg, Emma Hintz, Devin Champagne, Amaneet Lochab, Markus Brown, Jesse Abhyankar, Jasper Braun, Michelle Dinh, María Antonia Fortuño, María-del-Mar Ocón, Andrea Pasquier, Inés María Luque, Christopher W. Seder, Jeffrey A. Borgia, Luis Miguel Seijo, Luis M Montuenga, Roman Yelensky

AACR Annual Meeting 2024

GIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation

Hongyi Zhang, Xiaowei Zhan, Bo Li 

Nature Communications, 12: 4699 (2021)

De novo prediction of cancer-associated TCRs for non-invasive cancer detection

Daria Beshnova, Jianfeng Ye, Oreoluwa Onabolu, Benjamin Moon, Wenxin Zheng, Yang-Xin Fu, James Brugarolas, Jayanthi Lea, Bo Li 

Science Translational Medicine, 12, Issue 557 (2020)

Investigation of antigen-specific T cell clusters in human cancers

Hongyi Zhang, Longchao Liu, Jian Zhang, Jiahui Chen, Jianfeng Ye, Sachet Shukla, Jian Qiao, Xiaowei Zhan, Catherine Wu, Yang-Xin Fu, Bo Li 

Clinical Cancer Research, 26(6):1359-1371 (2020)

AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data

Christina Wong, Bo Li 

Bioinformatics, 8(2):589-591 (2022)

T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies

Mingyao Pan, Bo Li  

eLife, DOI:10.7554/eLife.81952 (2022)

Ultrasensitive detection of TCR hypervariable region in solid-tissue RNA-seq data

Bo Li, Taiwen Li, Binbin Wang, Ruoxu Dou, Jun S Liu and X. Shirley Liu  

Nature Genetics, 49(4):482-483 (2017)

Landscape of tumor-infiltrating T cell repertoire of human cancers

Bo Li, Taiwen Li, Jean-Christophe Pignon, Binbin Wang, Jinzeng Wang, Sachet Shukla, Ruoxu Dou, Qianming Chen, F. Stephen Hodi, Toni K. Choueiri, Catherine Wu, Nir Hacohen, Sabina Signoretti, Jun S. Liu and X. Shirley Liu

Nature Genetics, 48:725–732 (2016)